The electroretinogram (ERG) is the most direct and objective test available for evaluating the function of the retina. Electrodes are placed on the skin around the eye and a soft gold foil electrode is positioned over the lower lid to be in contact with the cornea through the tear film. This is readily tolerated by adults and children as young as 4 years old. Babies can be tested with electrode taped to the lower lid. Flashes of light are presented under the dark and light adapted conditions to separate the rod (night vision) and cone (colour vision) systems of the retina. Both the timing and the size of the ERG responses give valuable information about the extent and nature of the retinal abnormalities.

By changing the stimulus to a flickering chequer-board pattern on a TV monitor screen a pattern ERG is obtained. The resulting waveform reflects central vision or macular function and enables diagnosis and a quantitative assessment of early macular disease as well as the differentiation between localized macular disease and more widespread retinal disease.

The ERG has been the gold standard for evaluating night blindness, pigment changes in the retina, and color vision disorders, enabling the diagnosis of inherited retinal diseases before changes are seen in the eyes. It is also recognized as an important tool for the diagnosis and management of a wide range of common retinal diseases. The ERG can help to distinguish peripheral retinal disease from diseases localized to the central retinal or optic nerve.

The ERG is being used increasingly to identify vision-threatening changes in diabetes and in central retinal vein occlusions. The potential of the retina can be assessed through opacities such as advanced cataracts, vitreous hemorrhage or in eyes after severe trauma and early toxic damage from various causes involving the retina can be detected with the flash ERG or pattern ERG.

Ophthalmic Electro-Diagnostic Test

Test Name Area Tested Time Taken Dilating Drops
Flash ERG Global Retina(rods and cones) 60 minutes Yes
Pattern ERG Macular (central retinal) function 30 minutes No
EOG Retinal Pigment epithelium 30 minutes No
Cortical VEP Visual pathway (optic nerve to visual center in brain) 45 minutes No

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