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818-552-5040
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Kent W. Small, MD

Board-Certified: American Board of Ophthalmology

Fellowship: Vitreoretinal Diseases and Surgery, Duke University Eye Center, Durham, NC; Molecular Genetics, Duke University School of Medicine, Durham, NC

MD: Tulane University School of Medicine, New Orleans, LA

Specialized care for retinal diseases:

  • Macular degeneration
  • Diabetic retinopathy
  • Retinal tears & detachments
  • Inherited retinal diseases
  • Retinal vascular disease
  • Macular holes
  • Macular puckers
  • Macular edema
  • Proliferative vitreoretinopathy/scar tissue

State-of-the-art diagnostic exams:

  • Fluorescein & indocyanine green (ICG) angiography
  • Fundus photography
  • Scanning laser ophthalmoscopy (SLO)
  • Ultrasound A & B scans
  • Visual field testing
  • Microperimetry
  • Optical coherence tomography (OCT)

Photodynamic Therapy for Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a deterioration or breakdown of the macula. The macula is a small area at the center of the retina in the back of the eye that allows us to see fine details clearly and perform activities such as reading and driving. In exudative or “wet” AMD, abnormal blood vessels can grow in a layer beneath the retina, leaking fluid and blood and creating distortion or a large blind spot in the center of your vision.

Photodynamic therapy (PDT)—an outpatient procedure involving the use of a special light-activated drug—is used to treat some patients with wet AMD. PDT causes fewer visual side effects than other treatments. The benefit of PDT is that it inhibits abnormal blood vessel leakage associated with wet macular degeneration, limiting damage to the overlying retina.

With PDT, the inactive form of the drug is usually injected into a vein in the arm, where it travels to and accumulates in abnormal blood vessels under the center of the macula. A special low-intensity laser light targeted at the retina activates the drug only in the affected area, damaging the abnormal blood vessels under the retina and leaving normal blood vessels intact.

Patients who are treated with PDT will become temporarily extra sensitive to bright light (photosensitive). Care should be taken to avoid exposure of the skin or eyes to direct sunlight or bright indoor light for several days.

PDT therapy is not effective for treatment of atrophic or “dry” AMD, which is caused by aging and thinning of the tissues of the macula. Although hotodynamic therapy can preserve vision for many people, it may not stop vision loss in all patients. The abnormal blood vessels may regrow or begin to leak again. Every three months, patients must undergo a repeat examination that includes a fluorescein angiogramdye test. Multiple PDT treatments sometimes are necessary.

Cedars-Sinai medical towers | 8635 West 3rd Street, Suite 395-W, Los Angeles, CA 90048 | Tel: (310) 659-2200 | Fax: (310) 659-2822 Glendale Office | 501 North Orange Street Suite 250, Glendale, CA 91203 | Tel: (818) 552-5040 | Fax: (818) 552-5044

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